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- Reveille JD,Schrohenloher R,Acton RT,et al.DNA analysis of HLA,DR and DQ genes in American black with systemic lupus erythematosus.Arthritis Rheum,1989,32:1243,1251. 彭学标,徐文严,岳晓玉,等.;江苏籍汉族系统性红斑狼疮与HLA,DR基因的相关性研究
- HLA DR Ag was strongly expressed on activated T cells,macrophages. 巨噬细胞、T淋巴细胞高表达HLA DR抗原 (P <0 0 5 )。
- Study of Expression of HLA DR Antigen on Peripheral Lymphocytes in Patients with Mycosis Fungoides. 蕈样肉芽肿患者外周血淋巴细胞HLA-DR抗原表达的研究
- The HLA DR expression was 11.1% in M 3 AML cases, lower than that in the other types of AML cases ( 76.3% ) (P< 0.01 ). HLA DR抗原在M 3的表达频率为 1 1 .;1%25;低于其它类型AML病人的HLA DR阳性率 (76
- By comparison,the increase of HLA ABC antigen was slow,while the raise of HLA DR antigen was fast. 且两种细胞的HLA-ABC抗原表达量增高幅度较小,而HLA-DR抗原增高幅度较大。
- The acute rejection of the pationts with HLA DR 0 mismatching was only 5.26%, comparing with 20.36% in the pationts with HLA DR complete mismatching. HLA DR抗原的 0错配所发生急性排斥的占 5 .;2 6%25;HLA DR抗原完全错配的占 2 0
- These data suggest that there exists abnormality of the expression of HLA DR in MF PBL,which may be correlated with pathogenesis of MF. MF患者外周血淋巴细胞HLA?DR抗原表达普遍存在异常,与MF的发病密切相关。
- There was significantly more extensive HLA DR antigen expression in gastric epithelia in cagA + patients than that existed in cagA - patients. 感染cagA+ 菌株患者较感染cagA-株者胃上皮HLA DR抗原表达更明显 ;
- Results:36 cases with RPU were diagnosed and HLA DR Ag was strongly expressed on activated T cells, macrophages,epithelia and vascular endothelia in RPU tissues. 结果 :RPU组溃疡粘膜经组织病理学检查均符合 RPU的诊断 ,病变粘膜中巨噬细胞、T淋巴细胞、上皮细胞、血管内皮细胞异常表达 HLA- DR抗原。
- Serum TPOAb level and distribution of HLA DR antigen and dendritic cells showed the same ascending tendency following the aggravation of lymphocyte infiltration. 血清TPOAb水平及HLA DR抗原、树突状细胞分布随甲状腺组织淋巴细胞浸润程度加重呈逐渐增多趋势。
- Serum TPOAb level was determined, and HLA DR antigen, dendritic cells and lymphocytes in the thyroid gland tissue were observed in these same AITD patients. 用此方法检测一批自身免疫性甲状腺疾病 (AITD)患者血清TPOAb ,用病理学方法观察同批患者甲状腺组织中HLA DR抗原、树突状细胞及淋巴细胞浸润程度。
- Methods:Immunofluorescent three color flow cytometry was used to study the expression of CD69 and HLA DR on T lymphocytes in 30 patients with CA and 31 normal controls. 方法 :采用免疫荧光三标记流式细胞术检测 30例CA患者外周血T细胞CD6 9和HLA DR抗原的表达 ,并以 31例正常人作为对照。
- These results suggest that aberrant increase of dendritic cells and aberrant expression of HLA DR antigen on TEC may have a close relation to the initiation and/or maintenance of thyroid autoimmune reaction. 这说明DC异常增多、TEC异常表达DR抗原可能与甲状腺自身免疫反应的启动和(或)延续有密切关系。
- The results showed that the expression of HLA DR antigens on lesional keratinocytes (KCs) could be observed in SLE (6/16) and DLE (8/19), but not in normal skin . Most of the keratinocytes expressing HLA DR antigens were basal cells. 观察到正常人皮肤角质形成细胞未见HLA?DR抗原表达,而SLE(6/16),DLE(8/19)皮损处角质形成细胞可以表达HLA?DR抗原。
- The results showed that the expression rate of CD8,HLA DP,HLA DR in patients with both stromatic and ulcer herpetic keratitis,also CD10 in stromatic herpetic keratitis, were higher than in normal people. 结果显示HSK基质型与溃疡型CD8、HLA?DP、HLA?DR抗原表达阳性细胞明显高于正常人,基质型CD10也高于正常人。
- The expression rates of CD 34 and HLA DR were 3.6% and 31% in the chronic phase, 36% and 73% in acceleration phase, 62% and 100% in blastic phase, respectively. Both CD 34 and HLA DR were significantly higher in blastic phase than chronic phase (P<0.05). CML慢性期、加速期、急变期 CD34 及 HL A- DR抗原表达阳性率分别为 3.;6%25和 31%25;36%25和 73%25;6 2%25和 10 0%25;慢性期与急变期相比差异有统计学意义 ( P <0
- Methods 24 HIV 1 infected patients and 13 normal controls were tested and a three color flow cytometry was used to detect the activation marker HLA DR and the coreceptor CCR5, CXCR4 expressions in blood samples taken from the patients and the controls. 方法 用三色标记法流式细胞术检测 2 4例HIV 1感染者及 13例健康对照的抗凝血标本 ,分析活化标志物HLA DR及第二受体CCR5、CXCR4的表达等指标。
- Methods The number and the distribution of HLA DR +,S 100 + and CD1a + cells on synovial membranes in 25 patients with rheumatoid arthritis were investigated with immunohistochemical staining. 方法 采用免疫组织化学方法观察 2 5例RA滑膜中HLA DR抗原阳性表达细胞、S 10 0阳性CD1a阳性的树突状细胞(DC)的多少和分布情况。
- Before SMU3 and SMU8 therapy, there was the reverse of T cell subsets CD4/CD8 ratio and higher expression of the HLA DR antigen on the lymphocytes surface, which were normalized after SMU3 and SMU8 therapy. 治疗后CD+4/CD+8比例及HLA?DR抗原表达恢复正常。
- The immunophenotyping usually reveals the non expression in T, B lineage, while the myeloid lineage expressions are polymorphic, but only in a few APL cases the HLA DR antigen may be in low expression. 免疫表现为不表达T、B淋巴细胞抗原性,粒系抗原表达呈多态性,但部分病例HLA-DR抗原呈阳性或低表达。