Heparanase is the only mammalian heparan sulfate-degrading enzymes;it could cleave heparan sulfate(HS)which links to heparan sulfate proteoglycans (HSPGs).

• 摘要乙酰肝素酶是目前发现的哺乳动物细胞中唯一能切割细胞外基质中硫酸肝素蛋白多糖侧链的内源性糖苷酶。