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- OBJECTIVES: To improve the effect and safety of high dose methotrexate (HD-MTX) chemotherapy, the metabolic regularity of MTX and its clinical application were discussed. 目的:本研究对小儿急性淋巴细胞白血病大剂量甲氨蝶呤化疗时甲氨蝶呤血药浓度的变化规律及其临床应用进行探讨,旨在为提高临床化疗的有效性和安全性。
- Leucovorin rescue after continuing infusion of high dose methotrexate 大剂量氨甲蝶呤持续静脉滴注后四氢叶酸钙解救方案的研究
- Study of pharmacokinetics in cerebrospinal fluid during high dose methotrexate chemotherapy 大剂量甲氨蝶呤化疗的脑脊液药代动力学研究
- Keywords High dose methotrexate;Central nervous system leukemia;Serum concentration;CSF concentration; 大剂量甲氨蝶呤;中枢神经系统白血病;血药浓度;脑脊液浓度;
- Women, perhaps, could hazard a higher dose. 而女性呢,也许可以冒险试试更高一点的剂量。
- Can Sequential Administration Minimise the Cost of High Dose Chemotherapy? 循序行政管理能使高剂量化疗成本最小化吗?
- LDD ultra shallow junction can be reachec by low energy and high dose implant. 可以通过低能量,高剂量的等离子注入来实现LDD超浅结(ultra shallow junction)。
- Stikac,AndersonL,Frederiksen M.Single dose methotrexate for the treatment of ectopic pregnancy, Northwestern Memorial Hospital three-year experience.Am J Obstet Gynecol,1996,174(6):1840. 刘伯宁;孙剑英;陶文琪;等.;米非司酮配伍米索前列醇终止早孕1774例分析
- Melamine in high doses can disease kidney. 大剂量的三聚氰胺会导致肾病。
- I forgive those ancestors who participated in the mass marketing of high dose supplements causing humans to become paranoid. 我意愿原谅参与大量营销那些令人类变得偏执狂的、高剂量营养补充品的所有祖先。
- For acute effect, accidentally exposure for high dose of lead may cause abdominal pain and vomiting. 人体意外地接触高浓度的铅量,可导致急性中铅毒,病徵包括腹痛及呕吐。
- The lesion being treated receives a high dose of radiation with minimum risk to nearby tissue and structures. 病变接受高剂量射线的治疗,而临近组织结构却没有损伤。
- High dose arginine (5 grams per day given for 6 weeks) has been shown to improve erection in men with ED. 高剂量的精氨酸(每天5克,持续6星期)被证明对ed患者有显著疗效。
- The distance from the region of high dose to that of high gradient is within 4 mm. 计划/胶片分析得到高剂量、高梯度区域的距离差别均在4mm以内;
- Method: Administer high dose ( 3. 0g. kg-1) and low dose (1.0g. kg-1) ACTS to test animal. 方法:我们用3.;0g·kg~(-1)和1
- Methods: A high dose(3.0/kg),a middle dose(1.5/kg) and a low dose(0.75/kg) of WWT in experimental animals were studied. 方法:用五味藤浸膏3.;0g/kg、1
- High dose group of SYD, low dose group of SYD, Tongxinluo group,Herbesser group, Control group and Model group. 结果经导管拉伤加高渗液损伤后,动脉内膜被覆单层内皮细胞,内膜不规则增厚,血管平滑肌增生。
- Methods The mice were treated by low dose MMC before or after treated by high dose X-ray. 方法小鼠腹腔注射低剂量MMC,再给大剂量X射线照射,或先给大剂量X射线照射再给低剂量MMC。
- The long term effects of high dose chemotherapy with PBSCT still need further study. 然而其中四例经平均天数223天复发后死亡,另外三例仍持续在缓解中。
- Light fatty degeneration was found in liver cells of mice in higher dose group. 高剂量组小鼠可见肝细胞轻度脂肪变性。