However, R-verapamil (R-VPM),the isomeride of VPM is able to reversel MDR more effectively and safly, and has good perspective in clinical application.

• 从维拉帕米分离出的光学异构体R-型维拉帕米，在逆转肿瘤MDR时，更加高效安全，具有良好的临床应用前景。