Human macrophage elastase (HME;MMP-12) was first identified as an elastolytic metalloproteinase secreted by inflammatory macrophages 30 years ago.

• 三十年前，由炎症巨嗜细胞分泌的一种金属蛋白酶被发现，并命名为人类巨嗜细胞弹性蛋白酶(HME，MMP-12)。