ICAM-1 and MMP-9 may play a synergistic role in the occurrence, development and malignance in glioma. Hence, it is a better way to estimate and judge the malignant biological behavior of glioma by combined detection of ICAM-1 and MMP-9.

• ICAM-1和MMP-9在胶质瘤存在协同作用,共同参与胶质瘤的发生、发展和恶性演变,并由此推测ICAM-1与MMP-9联合检测会更好地对脑胶质瘤的恶性生物学行为进行评价和判断。