ICP do harm to both mother and fetus, especially to the perinatal neonates, and induces higher frequency of preterm labor, fetal distress, unexplained fetal death and stillbirth.

• 其对母婴均有不良影响,尤其对围生儿危害更大,可导致早产、胎儿窘迫、死胎、死产率增高等一系列产科并发症。