If an intervention is hoped to reduce mortality (ie, the endpoint is overall survival) from 30% to 15%, the risk ratio is 2, with a binomial sample size calculation of 320.
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- 如果介入是有望于将死亡率(例,终点是总存活数)从30%25减小至15%25,风险比率是2,采用320的二项式样本量计算