In a small study of patients taking an average of 4 anti-hypertensive medications, adding an MRA lowered blood pressure on average by an additional 25 mm Hg systolic and 12 mm Hg diastolic.

• 摄入平均4种抗高血压药物的小样本研究发现，联用一种MRA可以平均降低收缩压25mmHg和舒张压12mmHg。