In addition to direct effects on T cell activation,1,25-Dihydroxyvitamin D3 and its analogue modulate with different mechanisms the phenotype and function of antigen-presenting cells(APC),and,in particular,of dendritic cells(DC).

• 1,25-二羟维生素D3及其类似物除了直接作用于T细胞外,还通过各种机制调节抗原呈递细胞的表型和功能,尤其是树突细胞。