In mice, for instance, delivery of melatonin increases the risk of tumor development, and the overproduction of growth hormone leads to kidney problems, premature heart and lung failure, and an increased probability of early death.

• 譬如在小白鼠身上，给予褪黑激素会增加肿瘤发生的风险，而生长激素过量，也会造成肾脏问题、心脏与肺脏发育不全，以及增加早夭的机率。