In our experiment, genistein lead to a decrease in [Ca2+]i of TMC, so inferring that it can relax the trabecular meshwork ,which can lead to the increase of outflow facility.

• 本试验中genistein作用于小梁细胞后引起[Ca2+]i呈剂量依赖性降低，由此认为genistein通过降低小梁细胞[Ca2+]i，从而松弛小梁网，促进房水流出。