In the article,we introduced focally the origin of circulating fetal DNA,its fundamental characteristics and application of detection for it in prenatal diagnosis.

• 本文介绍了胎儿游离DNA的来源、生物学特点及在产前诊断中的应用,胎儿游离DNA具有含量高且产后很快清除等优点,有广泛的临床应用价值。