In the first chapter of this thesis, we discuss the synthesis of Kaitocphalin, the first natural antagonist of AMPA/KA receptor, which isolated from marine alga in 1997 by Japanese chemists.

• Kaitocephalin 是日本化学家在1997年，从海洋藻类生物中分离得到的第一个AMPA/KA 受体拮抗剂。