In tumours with wild type of KRAS, the protein is tightly controlled and only activated under certain conditions, which allows the monoclonal antibody Erbitux to block signals in the EGFR pathway.

• 含野生型KRAS基因的肿瘤，该蛋白质受到严密的控制、仅在某些条件下被激活，从而允许单克隆抗体爱必妥阻止EGFR途径中的信号。