Interleukin 4 can reverse the multi drug resistance by inhibiting the expression of p gp and increasing the quantity of intracellular chemotherapeutic agents in tumor cells. The effects were probably related to the inhibition of the PKC activity.

• IL 4可通过抑制肿瘤细胞的p gp表达 ,增加化疗药物在肿瘤细胞内的聚集而逆转白血病细胞的MDR ,此作用可能与?