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- METHODS An animal model of rabbit invasive aspergillosis was established. 方法建立兔侵袭性烟曲霉感染动物模型;
- Combination therapy was used as primary therapy for invasive aspergillosis in 47%, and as salvage in 80%. 47%25的侵袭性曲霉菌感染患者采用联合治疗作为首选,80%25的患者作为补救治疗。
- Voriconazole is recommended for the primary treatment of invasive aspergillosis in most patients (A-I). 伏立康唑被推荐用于大多数侵袭性曲菌病患者的首要治疗措施(A-I)。
- Management of breakthrough invasive aspergillosis in the context of mould-active azole prophylaxis is not defined by clinical trial data. 在现行的唑类药物预防的模式背景下,没有通过临床实验资料定义侵袭性曲菌病的突破性治疗。
- OBJECTIVE To study the etiological diagnosis of invasive aspergillosis by the monoclonal antibodies against Aspergillus fumigatus. 目的探讨自行研制的抗烟曲霉单克隆抗体在兔侵袭性烟曲霉感染动物模型中的应用。
- Early content of GM protein was high in infected animal models and serum and body fluid of patients of invasive Aspergillosis. 在感染的动物模型和侵袭性烟曲霉病患者血清和体液中早期GM蛋白含量即可增高。
- Of the two newer triazoles, voriconazole has been recommended in international guidelines as primary therapy for acute invasive aspergillosis. 两个新的三唑类当中,国际指南推荐伏立康唑作为急性侵袭性曲霉病的初始治疗。
- With the expanding of immunocompromised population in hospitals, the incidence of invasive aspergillosis has risen year by year. 随着院内免疫缺陷人群的增多,侵袭性曲霉病的发病率逐年增加。
- In patients with acute leukemia who have early invasive aspergillosis, CT predictably shows a "halo" of ground-glass opacity surrounding focal dense parenchymal nodules. 在急性白血病患者患侵袭性曲菌病早期,CT表现为毛玻璃样阴影呈光晕样包绕局灶性高密度结节。
- The largest randomized controlled trial demonstrates that voriconazole is superior to deoxycholate amphotericin B (D-AMB) as primary treatment for invasive aspergillosis. 最大的随机化对照实验证实伏立康唑优于脱氧胆酸二性霉素B(二性霉素B为侵袭性曲菌病的主要治疗措施)。
- The largest randomized controlled trial demonstrates that voriconazole is superior to deoxycholate amphotericin B (D-AM as primary treatment for invasive aspergillosis. 最大的随机化对照实验证实伏立康唑优于脱氧胆酸二性霉素B(二性霉素B为侵袭性曲菌病的主要治疗措施)。
- Combination of Voriconazole and Caspofungin as Primary Therapy for Invasive Aspergillosis in Solid Organ Transplant Recipients: A Prospective, Multicenter, Observational Study. 背景:联合应用伏立康唑和卡泊芬净作为器官移植患者侵袭性曲霉感染的基础性治疗方法的疗效尚未进行研究。
- The role of combination therapy in the treatment of invasive aspergillosis as primary or salvage therapy is uncertain and warrants a prospective, controlled clinical trial. 侵袭性曲菌病的联合药物治疗是作为首选还是难治尚无定论,需要一个前瞻性对照临床实验进行证实。
- Based on the strength of the randomized study, the panel recommends voriconazole for primary treatment of these very uncommon manifestations of invasive aspergillosis (B-III). 在随机研究的力度的基础上,专家组推荐伏立康唑作为这些少见部位侵袭性曲菌病的用药首选。
- In evaluating such patients, the diagnosis of invasive aspergillosis should be established if it was previously uncertain and should be confirmed if it was previously known. 在对这些侵袭性曲菌病患者的评价当中,如果原来诊断不明,就应该初步诊断;如果原来曾作出诊断,就应该得到确诊。
- Disseminated invasive aspergillosis is a serious and potentially lethal infectious complication of immunosuppressed individuals, including transplant recipients. 对于包含器官移植受者在内的免疫抑制个体,弥漫性侵袭曲霉菌感染是致命的感染性并发症。
- Although both anidulafungin and micafungin are approved for treatment of candidiasis, their role in invasive aspergillosis requires more clinical trial evaluation. 虽然阿尼芬净和米卡芬净已批准用于念珠菌感染的治疗,它们在侵袭性曲霉菌病治疗中的作用还需要更多的临床试验来评价。
- We sought to determine the approach to antifungal prophylaxis, and diagnostic and therapeutic practices for the management of invasive aspergillosis in liver transplant recipients. 我们在此探寻肝移植受者侵袭性曲霉菌感染的预防、诊断以及治疗。
- This document reviews guidelines for management of the 3 major forms of aspergillosis: invasive aspergillosis, chronic (and saprophytic) forms of aspergillosis, and allergic forms of aspergillosis. 该文件综述了三种主要类型曲菌病的治疗指南:侵袭性曲菌病,慢性寄生性曲菌病和过敏性曲菌病。
- Keywords Liver transplantation;Risk factors;Invasive aspergillosis; 肝移植;危险因素;侵袭性曲霉病;