It is concluded that LOH at MCC,DCC and YNZ22 loci may be involved in carcinogenesis of gastric cancer and LOH at DCC genetic locus may be related to prognosis of patients with gastric cancer.

• 结果提示，MCC、DCC基因和YNZ22位点LOH参与了胃癌的发生与发展，DCC基因LOH可能与预后相关。