It was further found that AK auto Ab can significantly inhibit the proliferation of KC and the production of IL-6 and IL-8 by KC, and induce apoptosis of KC cultured in vitro.

• 我们曾采用亲和层析的方法成功地自正常人血清中纯化了AK autoAb，并进一步发现，AK auto Ab能够抑制培养KC的增殖代谢，可以抑制KC产生免疫介质如IL-6、IL-8，促进KC凋亡。