JNK signaling pathway may play an important role in the apoptosis of Eca-109 cells following COPADG treatment.

• JNK信号转导通路在COPADG诱导Eca-109细胞凋亡过程中发挥重要作用；COPADG通过JNK信号通路诱导Eca-109细胞凋亡.