Keywords Cephalosporin C;Cephalosporium acremonium;strain screening model;continuous mutagenesis;Uniform Design;porous polymeric adsorbents;desorption;spray drying;

• 头孢菌素C;顶头孢霉;菌种筛选模型;连续诱变;均匀设计;大孔吸附树脂;解吸;喷雾干燥法;