Keywords TK gene mutation assay;aneuploidy;TK6;TKE-E6;normal growing colony;slow growing colony;LOH;STR;karyotype;

• TK基因突变试验;非整倍体;TK6;TK6-E6;正常生长集落;缓慢生长集落;杂合性丢失;短串联重复序列;核型分析;