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- Keywords Glaucocalyxin A;Liver microsome enzyme;Drug metabolism;High performance liquid chromatography; 蓝萼甲素;肝微粒体酶;药物代谢;高效液相色谱法;
- Liver microsome enzyme 肝微粒体酶
- After induced by AFB1 the activity of liver microsomal enzymes in duck has been studied and has been compared with the control groups respectively. 本文对1月龄麻鸭经过黄曲霉毒素诱导后在1月、1年及3年观察其肝微粒体酶(S9)的代谢活性并与各相应对照组进行比较。
- Results and Conclusion : The result s both with and without S9 (rat liver microsomal enzymes) showed that all the samples had no mutagenicity. 结果与结论:经加和不加大鼠肝脏微粒体酶(S9) 两种试验,结果全部受试物均未发现致突变毒性;
- Phenobarbital does not impair normal hepatic function but has been shown to induce liver microsomal enzymes, thus increasing and/or altering the metabolism of barbiturates and other drugs. 苯巴比妥不损害肝脏的功能,但可诱导肝微粒体酶,从而增加或改变巴比妥类和其他药物的代谢。
- In this study, we investigated its metabolism by use of rat liver microsome in vitro. 利用大鼠肝微粒体对新农药多噻烷进行体外代谢研究。
- The Bradford method was used to measure the concentration of protein in liver microsome, and activities of cytochrome P450 enzymes were determined by the spectrophotometer method. 测定一月龄至八月龄不同性别的猪,肝微粒体蛋白含量、CYP450含量、CYPb5含量、NADPH-细胞色素C还原酶活性、氨基比林-N-脱甲基酶活性、红霉素-N-脱甲基酶活性和苯胺-4-羟化酶活性。
- Antioxidant activities of extractions were determined by chemical methods to produce superoxide free radicals, hydroxide free radicals and lipid peroxide of rat liver microsome. 采用化学方法产生超氧阴离子自由基、羟自由基和小鼠肝匀浆液脂质过氧化体系对提取物进行抗氧化活性检测,研究其清除自由基和抑制脂质过氧化能力的差异。
- The proper conditions for testotesrone metabolism in liver microsome system included substrate concentration, incubation time, pH and incubation temperature. 方法:采用超高速离心法制备大鼠肝脏微粒体,建立体外肝脏微粒体混合酶代谢体系。
- According to recent materials,Introduce liver microsome incubations in vitro,liver cell incubations in vitro,isolated perfused liver and liver slices,respectively. 对近几年的文献资料进行分析、综合、归纳。
- Effects of interactions between captopril and low-dosage aspirin on experimental myocardial ischemia and the activity of liver microsomal enzymes in rats 卡托普利和低剂量阿司匹林相互作用对大鼠实验性心肌缺血及肝微粒体酶活性的影响
- Cytochrome P450 2D6 (CYP2D6) is an important hepatic microsomal enzyme which metabolizes clinical drugs. CYP2D6在临床重要药物代谢中具有重要作用。
- Keywords Puerarin;Liver microsome;Cytochrome P450; 葛根素;肝微粒体;细胞色素P450;
- liver microsomal enzymes 肝微粒体酶
- In vitro the experimental results showed that fluoride could significantly increase the content of lipid peroxide (LPO) of rat liver microsome, and the lipid peroxidation was antagonized by adding selenium to liver microsomal system simultaneously. 体外实验结果表明,加氟可使微粒体系统脂质过氧化物(LPO)含量显著增加; 同时加硒可结抗氟致微粒体系统的脂质过氧化作用。
- Keywords fenfluramine;enantiomer;liver microsome;metabolism; 芬氟拉明;对映体;肝微粒体;代谢;
- Keywords anti-parasitic;cytochrome P450;liver microsome; 抗寄生虫;细胞色素P450;肝微粒体;
- Keywords cytochrome P450;probe;injection bupleuri;liver microsome; 细胞色素P450;探针药物;柴胡注射液;肝微粒体;
- Preliminary data indicate that steviol may be activated to a mutagenic metabloite by human liver microsomes. 初步数据显示,甜菊醇可能经人体的肝脏微粒体活化成引致基因突变的代谢物。
- Induction of microsomal enzyme activity 药酶诱导作用