METHODS: The young SD rats(5-6 months)and the aged animals(20-21 months)were subjected to 3h of middle cerebral artery occulsion with the intraluminal filament technique, followed by 1d, 3d, 6d and 12d of reperfusion.

• 方法:SD雄性青年(5-6月龄)和老龄(20-21月龄)大鼠, 随机分为青年假手术组(青年SO)、青年模型组、老龄假手术组(老龄 SO)、老龄模型组,模型组分为I3h、I/R1d、3d、6d、12d时间点。