METHODS: Using electrophysiologic method to study the changes of ECOG and power spectrum, NFLX concentrations of blood and brain areas of rats were detected with HPLC.

• 方法：以电生理方法研究大鼠iv诺氟沙星100mg/kg后的脑电图、脑电功率谱变化，以HPLC法测定大鼠血及脑组织中的诺氟沙星浓度。