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- Thus, the suppression of MMP activity with MMP inhibitors was the focus of oncologic research and drug development. 因此用MMP抑制剂抑制MMP的活性就成为肿瘤学和药物研发的焦点。
- To evaluate the in vitro activity of MMPs is important in diagnosis and provention of cancer and provides the basis for choice of MMPs inhibitors. 在体外测定基质金属蛋白酶的活性水平,对恶性肿瘤的诊断和预防具有重要意义,同时为小分子基质金属蛋白酶抑制剂的活性筛选提供有益的依据。
- At the same time, synthesized MMPs inhibitors (MMPI) failed to inhibit the progressive lung cancer in foreign clinical trials. 同时，国外对于人工合成的MMPs抑制剂（Matrix Metalloproteinases Inhibitor, MMPI）进行了临床试验，表明其在进展期肺癌的治疗中并无明显意义。
- RECK gene, a new MMP inhibitor, is able to inhibit MMPs to inhibit the invasiveness and metastasis of the malignancies. RECK基因是近年发现的新型基质金属蛋白酶(MMP)抑制剂,研究表明,其可在转录后水平抑制多种MMP的表达,抑制肿瘤血管形成,从而抑制肿瘤的侵袭及转移。
- Finally, 2- alkylthio-4-arylsulfanilamidepyrimidine-5-hydroxamates as a novel kind of MMP inhibitors were obtained.All compouds were tested in vitro for the inhibition of MMP-16. 本论文的第二章便是通过对反应路线的摸索和设计，最终合成出一类新型的2-烷巯基-4-芳香磺胺嘧啶-5-异羟肟酸类抑制剂。
- RECK gene, a new MMP inhibitor, is able to inhibit MMPs to inhibit the invasiveness and metastasis of the malignancies. Update on the research of the RECK gene was summarized. RECK基因是近年发现的新型基质金属蛋白酶(MMP)抑制剂,研究表明,其可在转录后水平抑制多种MMP的表达,抑制肿瘤血管形成,从而抑制肿瘤的侵袭及转移。作者就RECK基因的研究进展作一综述。
- The reagents were 2 mmol/L APMA (MMP activator), 2 mmol/L EDTA, 100 mmol/L EDTA, 200 mmol/L EDTA, 0.2% and 0.02% chlorhexidine(MMP inhibitor),and the blank artificial salival was taken as control. 100、200mmol/L乙二胺四乙酸(EDTA)组,0·2%25、0·02%25醋酸氯己定组(MMP抑制剂); 以空白人工唾液作对照组。
- MMPs inhibitors 金属蛋白酶抑制剂
- MMP inhibitors 基质金属蛋白酶抑制剂
- MMPs inhibitor 金属蛋白酶抑制剂
- No crossreactivity with other MMPs. 概述 Recognizes human and mouse.
- In this thesis, the first chapter simply reviews MMPs and the investigation process of the inhibitors of MMPs . 本论文的第一章简单介绍基质金属蛋白酶及其抑制剂的研究现状。
- Conclusion MMP -9 could play an important role i... 结论MMP-9在膀胱病变中发挥重要作用。
- CL was a potent inhibitor of Ca 2+ ,Mg 2+ ATPase. 马桑内酯是Ca2＋，Mg2＋?ATP酶的强力抑制剂。
- Usually, Clr is binding to C1INH (Cl inhibitor). 补体组分C1r含有两个CUB结构域，一个EGF结构域和一个丝氨酸蛋白酶结构域，是一种丝氨酸蛋白酶原。
- Mouldproof wall paper, join mould inhibitor. 防霉墙纸，加入防霉剂。
- MMPs take part in these pr ocesses on various mechanisms. 临床上,基质金属蛋白酶对乳腺癌的治疗及预后的判断也有重要的价值。
- ECMs are degraded mainly by matrix metalloproteinsaes(MMPs). 基质金属蛋白酶是调节细胞外基质降解代谢的主要酶类。
- Rat Tissue factor pathway inhibitor,TFPI ... 大鼠组织因子途径抑制物(TFPI)ELISA Kit；
- Rabbit Tissue factor pathway inhibitor，TFPI... 兔组织因子途径抑制物（TFPI）试剂盒；
