Mediated by integrin,ILK participates in the deposition of ECM in the kidney of patients with IgA nephropathy,might play an important role in the pathogenesis at the early/medium stage of IgA nephropathy.

• ILK可能通过介导Integrin参与IgA肾病的异常细胞外基质的沉积,尤其在IgA肾病早中期起着重要作用。