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- MEM1 is an oncogene, and its upregulation influences metastatic potential. MEM1是致癌基因,它的上调影响癌细胞转移能力。
- They do not have the metastatic potential observed in testicular teratoma, and are cured by surgical resection alone. 纵膈腔之成熟畸胎瘤不像是睾九丸胎瘤可观察到的转移潜力且可经由单独外科切除治愈。
- Sloane BF,Dunn JR,Honn KV.Lysosomal cathepsin B:Correlation with metastatic potential[J].Science,1981,212:1151. 蒯小玲,萧树东,刘文忠,等.;重组组织蛋白酶B的表达与纯化[J]
- Objective To investigate the correlation between BRI gene expression and the metastatic potential in human non small cell lung cancer cell lines. 目的 研究BRI基因在人非小细胞肺癌细胞系中的表达 ,探讨其表达情况与肺癌转移能力的相关性。
- Objective To investigate the potential relationship between BRI gene expression and metastatic potential in human non-small cell lung cancer(NSCLC). 目的 探讨BRI基因在人非小细胞肺癌中的差异表达情况及其与肺癌发生及转移能力形成的相关性。
- Some cancers have limited invasiveness and metastatic potential, for instance, whereas others spread quickly to distant organs. 举例来说,有些人的癌细胞侵略性和转移力较低,有些人的癌症很快就扩散到其他器官。
- Shindo-Okada N,Takeuchi K,Han BS,et al.Establishment of cell lines with high and low metastatic potential from A549 human lung adenocarcinoma. 李新志;陈安民;郭风劲;等.;表达增强型绿色荧光蛋白的骨肉瘤细胞亚株建立及生物学特性
- Sequence-specific siRNA (OPNi-2) targeting OPN can significantly reduce OPN mRNA expression in HCC-LM3 cell line with highly metastatic potential. OPNi-2可以特异性抑制高转移肝癌细胞系(HCC-LM3)内OPN的表达。
- Colo 205 cells may have the higher metastasis potential. 大肠癌Co?lo?205 细胞可能具有较高的转移能力。
- Objective To investigate the sequence of amyloid fibrils (BRI) gene and its expression in two lung adenocarcinoma cell lines AGZY83-a and Anip973 with the same tumor origin but different metastatic potential. 目的 确认淀粉样纤维蛋白基因 (amyloid fibrils,BRI)基因在 1对同源但转移能力不同的肺腺癌细胞系 AGZY83- a和 Anip973中的序列并分析其表达。
- Methods DNA sequencing, sequential G banding fluorescence in situ hybridization (FISH) and Northern blot were used to analyze the sequence and expression of BRI gene was in two lung adenocarcinoma cell lines with different metastatic potential. 方法 采用测序技术 ,Northern印迹杂交 ,G显带后荧光原位杂交分析 BRI基因在肺腺癌细胞系的序列与表达。
- Methods Using the quantitative reverse transcription PCR procedure,we observed the expression of nm23 mRNA in human pancreatic cancer JF305 cell sublines with different metastatic potential. 方法 在建立不同转移潜能的人胰腺癌JF305 单克隆细胞亚系的基础上,应用定量逆转录多聚酶链式反应技术(RT?PCR)检测不同转移潜能的人胰腺癌JF305 单克隆细胞亚系细胞中nm23 mRNA 的表达。
- During the development of MDR, epithelial to mesenchymal transition induced by Twist may be related to the enhanced invasion and metastatic potential of multidrug resistant breast cancer cells MCF-7/ADR. 在多药耐药乳腺癌细胞MCF-7/ADR中,其侵袭力增强可能与Twist介导的EMT发生有关。
- In addition to such cancer-type-specific patterns, chromosome changes indicative of cancer stage, metastatic potential, and even drug resistance have also been identified by several research teams. 染色体的变化型态除了与癌症的种类具有特定相关外,还有好些研究团队指出,它们还可能是癌症分期、转移潜力,甚至抗药性的指标。
- An early and more accurate assessment of the metastatic potential of breast cancer and prognosis is of great significance to the clinical guidance for its timely and effective treatment. 如何能早期对乳腺癌的转移潜能及预后做出更为准确的评估,对于指导临床进行及时、有效的治疗具有十分重要的意义。
- HCCLM6 demonstrated stronger invasiveness and higher metastatic potential than HCCLM3, although the former had morphological and in vitro biological properties similar to those of the latter. HCCLM6的形态学和体外生物学特性与HCCLM3相似,但裸鼠体内接种后所表现的侵袭性和自发性转移特性又有了显著增强。
- Cancer stem cells(CSC) are defined as the unique subpopulation in the tumors,which can possess the ability to initiate tumor growth and sustain self-renewal as well as metastatic potential. 近年来的研究表明肿瘤中只有少量细胞具有发生肿瘤以及持续的自我更新能力,这类具有干细胞特性的肿瘤细胞被定义为肿瘤干细胞(CSC)。
- Using assays of metastasis in mice, we found that the recipient tumor cells acquired the metastatic potential of the transferred mtDNA. 当研究人员用这种杂交细胞对小鼠实施皮下注射后,这些细胞逐渐发育为肿瘤并最终扩散到肺。
- The up regulated expression of BRI 1.6 kb mRNA transcript may indicate the formation of metastatic potential of NSCLC. BRI is possibly a metastasis related gene. BRImRNA尤其是 1.;6kb转录本的表达上调与非小细胞肺癌转移表型的形成可能有一定关系
- Education develops potential abilities. 教育能开发人的潜能。