Method Orthogonal design is used to determine the relation of the amount as well as proportion of hydroxypropyl methylcellulose and Carbopol with in vitro release and adhesive force of the tablets.

• 方法采用正交设计方法,确定生物粘附材料羟丙甲纤维素、卡波姆的用量及配比与制剂体外释放度及粘附力的关系。