Method The drug plasma concentration was determined by HPLC, in vivo release profiles of nefopam from the nefopan hydrochloride-resin complexes and the nefopan hydrochloride tablets were compared.

• 方法 采用HPLC法测定了口服盐酸奈福泮药物树脂缓释后不同时刻家犬体内的血药浓度，并与口服盐酸奈福泮片的相比较。