Methods 577 patients with malignant tumor accepted therapy with Fluorouracil were randomly divided into four groups A,B,C and D.

• 方法将577例接受氟脲嘧啶类为主抗癌药物化学治疗的患者随机分为A、B、C、D组,A组口服别嘌呤醇片,3次/d;