Methods ATRA liposomes was prepared by reverse evaporating method and to determine the concentration and the entrapment efficiency of ATRA liposomes by HPLC.

• 方法采用逆相蒸发法制备全反式维甲酸脂质体,高效液相色谱法检测活性药物含量及包封率,并进行加速试验检测其初步稳定性。