Methods Septic shock model was replicated by cecal ligation and puncture(CLP). Ninety-six rats were randomly divided into sham operation group,CLP group,CLP+ hemin(Hm)group and CLP+zinc protoporphyrin(ZnPP)group.

• 方法采用盲肠结扎穿孔术(CLP)复制感染性休克模型,按随机数字表法将96只大鼠分为假手术对照组、CLP组、CLP+氯血红素(Hm)组和CLP+锌原卟啉(ZnPP)组。