Methods Spontaneously hypertensive rats(SHRs) and two kidney, one clip renovascular hypertensive(2K1C) rats were used in the experiment.

• 方法采用两种高血压模型即自发性高血压大鼠（SHR）和两肾一夹型（2K1C）肾血管性高血压大鼠，观察在高血压所致LVH的不同阶段，收缩压（SBP）、左室重/体重比（LVW/BW）及左心室c－fos基因表达水平的变化。