Methods We established rat cerebral ischemia models of bilateralcarotid communis artery occlusion with ligation,determined the leves of ET-1 in plasma and brain tissueof rats with cerebral ischemia before and after injection Mg2+ by RIA.

• 方法用双侧颈总动脉结扎法建立大鼠脑缺血模型，用RIA法测定注射Mg2＋前后脑缺血大鼠血浆及脑组织中ET－1含量。