Methods: On the basis of equitoxic dose (1/9 LD50), 26 mice with subcutaneous and cecal implanted tumors were treated with pingyangmycin mitomycin C (MMC), 5-FU, and the curative effects were compared.

  • 方法:应用小鼠结肠癌26 瘤株皮下移植和盲肠原位移植模型及裸鼠移植瘤模型,以1/9 半数致死量(LD50) 等毒性剂量观察PYM 的抗瘤活性,并与丝裂霉素C( MMC) 和5 -氟脲嘧啶(5 - FU) 进行比较。
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