Methods: The CHARISMA trial was a randomized trial comparing long-term 75 mg/day clopidogrel ersus placebo in patients with cardioascular disease or multiple risk factors on aspirin.

• 方法：CHARISMA试验是一项关于心血管疾病患者或对阿司匹林有多重危险因素的患者长期服用氯吡格雷75mg/d与安慰剂比较的随机试验。