Methods: The semi bionic extraction (SBE) conditions were optimized through homogeneous design while berberine, cinnamic acid, total alkaloids, volatile oil and dry extract were adopted as markers.

• 方法:以小檗碱、肉桂酸、总生物碱、挥发油、干浸膏量为指标,采用均匀设计优选其半仿生提取法(简称SBE法)的工艺条件。