Methods.Fifty-eight families with FIS were genotyped for the aggrecan exon 12 polymorphism using a polymerase chain reaction method.

• 方法：通过使用多聚酶链反应方法，对58个家族性特发性脊柱侧凸的家族进行聚集蛋白聚糖外显子12的多态现象进行了基因定型。