Microdialysis sampling coupled with high performance liquid chromatography and amperometric detector was developed and applied to determine Xanthine and Hypoxanthine in rat striatum.

• 采用微渗析活体取样技术和高效液相色谱安培检测法 ,测定了鼠脑纹状体中的黄嘌呤和次黄嘌呤。