Mild and moderately seere forms of ichthyosis are relatiely common disorders, but the harlequin fetus represents a rare, seere, and dramatic form of this disorder.

• 丑角样鱼鳞病的特点是胎儿皮肤角质层过度生长，轻或中度的鱼鳞癣形成是相对常见的畸形，但是这种畸形常比较少见、严重且戏剧化。