Moreover, the AMG, L-NAME and AMG+L-NAME groups significantly reduced NO2- contents in spinal cord & brain homogenate, but the L-Arg and AMG+L-Arg+LNAME groups elevated those in the acetic acid test of mice.

• AMG(100，200 mg .；kg一，)组脊髓和脑nNOS与c一FoS阳性神经元明显少于模型组; 平均光密度明显降低，AMG明显抑制脊髓和脑组织nNOS与c一Fos阳性表达。