Mouse models of this genetic defect have been unsatisfactory because homozygote null animals die early in development and heterozygotes do not exhibit a cardiac phenotype.
英
美
- 此种遗传缺陷的小鼠模式仍然不能令人满足,因其纯合体空白动物在发展中早期死亡,而杂合体不能显示心脏表型。