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- The new process of multidrug resistance reversal agents 肿瘤多药耐药逆转剂研究新进展
- Keywords Traditional Chinese medicine constituents;Multidrug resistance reversal;Vincristine; 中药成分;耐药逆转;长春新碱;
- Multidrug resistance reversal 耐药逆转
- Objective To study the reversal effects of droloxifene (DRO) on multidrug resistance (MDR) in MCF7/ADR and its mechanism. 目的:研究屈洛昔芬(DRO)对乳腺癌耐药细胞株(MCF7/ADR)多药耐药性(MDR)的影响。
- Multidrug resistance(MDR) has become the main hindrance of chemotherapy,and the reversal of MDR is the key point to improve curative effect of chemotherapy. 摘要 肿瘤细胞对化疗药物产生的多药耐药(MDR)已成为当前影响肿瘤化学治疗疗效的主要障碍,寻找低毒有效的MDR逆转剂是提高化疗疗效的关键。
- The aim of this study was to ex amine the reversal effects of high intensity focused ultrasound (HIFU) and co-a dministration with Adriamycin (ADM) on multidrug resistance (MDR) in HepG2/Adm c ells, and to investigate its mechanism. 本研究评价高强度聚焦超声及其联合阿霉素(Adriamycin,ADM)对人肝癌多药耐药细胞株HepG2/Adm的效应,并探讨其作用机制。
- AIM: To study the reversal effects of droloxifene (DRO) on multidrug resistance (MDR) in K562 cell line resistant to adriamycin (ADR). 目的:研究屈洛昔芬(DRO)对耐阿霉素(ADR)K562细胞株(K562/A02)多药耐药性(MDR)的逆转作用及逆转机制。
- Obsjective:To observe the reversal effect of Sangen Mixture(SGM) in multidrug resistant(MDR) cell lines K562/ADR and K562/VCR. 目的:研究三根制剂对多药耐药(MDR)细胞株的逆转作用。
- BACKGROUND & OBJECTIVE: Multidrug resistance is one of the main caus es of treatment failure of chemotherapy. 背景及目的:耐药性产生是化疗失败的主要原因之一,克服耐药性的方法之一是使用逆转剂。
- reversal of multidrug resistance 多药耐药逆转
- Expression of multidrug resistance gene in patients with maligant trophoblastic tumor and its clinical significance. 多药耐药基因在滋养细胞肿瘤组织中的表达及其临床意义。
- Objective To elucidate the multidrug resistance(MDR) in bladdertransitional cell carcinoma. 目的研究膀胱移行细胞癌的多药耐药性。
- However, multidrug resistance (MDR) presents an important obstacle for the success of the treatment. 对瘤组织而言,多药耐药是化疗失败的主要原因。
- The multidrug resistance rate of positive-integron isolates is far greater than the negative ones. 整合子阳性菌株对多种抗生素的耐药率远大于整合子阴性菌;
- The investigate of distribution of integron in multidrug resistance isolates in Jiaozhou Bay was carried out. 摘要为调查整合子在胶州湾水域多重耐药菌中的分布情况。
- The mechanism of bacterial efflux pumps is one of the important factors resulting in bacterial multidrug resistance. 细菌耐药性,尤其是多重耐药问题日益严重,给临床治疗带来极大的困难。
- However,the multidrug resistance (MDR) of nasopharyngeal carcinoma is the key role in the failure of the treatment. 而多药耐药(MDR)机制是导致其化疗等综合治疗失败的主要原因。
- Objective To explore the reversal effect of cyclosporin A(CsA) in combination with cytokines on multidrug resistant cell line K562/A02. Method The cytotoxicities of daunorubicin(DNR) were assayed by MTT method. 目的探讨环孢菌素A(CsA)联合细胞因子对耐药细胞系K562/A02的逆转作用。 方法以甲基四唑蓝法测定柔红霉素(DNR)的细胞毒性;
- Multidrug resistance to chemotherapeutic drugs is an important reason for clinical chemotherapy failure. 临床化疗失败的重要原因是肿瘤细胞对化疗药物产生多药耐药(MDR)。
- Conclusions The multidrug resistance (MDR) in endometrial carcinoma may be related with the expression of MDR1 gene. 结论子宫内膜癌对化疗的耐药可能是一种固有性MDR,这可能与MDR1基因的表达有关。