Multivariate analysis showed that genotype B of HBV, elevated pretreatment alanine amiotransferase (ALT) levels and low pretreatment HBV DNA load were the independent predictors of efficacy of IFN- a therapy in patients with chronic HBV infection.

• 经多因素分析发现B基因型、治疗前丙氨酸氨基转移酶(alanine amiotransferase,ALT)和血清HBV DNA水平是影响干扰素抗病毒应答的独立预测因素。