NK cell activation depends on the balance between activating and inhibitory signals, delivered by self-human leukocyte antigens (HLA) through binding of killer-cell immunoglobulin receptors (KIR).

• NK细胞活化主要依靠活化和抑制细胞的平衡，通过自身HLA绑定杀伤细胞免疫球蛋白受体（KIR）释放。