OBJECTIVE To prepare diclofenac sodium (DS) liposomal gel,and evaluate the pharmacokinetics and irritation of DS liposomal gel in rabbits after intramuscular administration.

• 目的制备双氯芬酸钠(DS)脂质体凝胶,考察其肌注后家兔体内的血药浓度经-时过程及对肌肉的刺激性。