OBJECTIVE To study the pharmacokinetics and tissue distribution of oxymatrine-SLN in animal and investigate the liver targeting effect of oxymatrine-SLN.

• 目的研究苦参素固体脂质体纳米粒(SLN)的动物体内行为,探讨苦参素SLN作为肝靶向给药系统的可行性。