OBJECTIVE To study the pharmacokinetics of omeprazole and its two main metabolites in 19 Chinese healthy identified as CYP2C19 EMs and 6 PMs.

• 目的 研究19名细胞色素氧化酶CYP2C19强代谢者和6名弱代谢者奥美拉唑及其代谢产物5-羟基奥美拉唑和奥美拉唑砜的药动学规律。