OBJECTIVE: Diabetes mellitus is an endocrinal-metabolic syndrome,which was mainly treated with hypoglycemic agents and antidiabetic agents,and each kind has different mechanism of action.

• 目的:糖尿病是一种内分泌-代谢综合征,治疗药物包括降糖药和抗糖尿病药,作用机制各异,而双胍类降糖药独树一帜,本文总结其优势和临床评价。